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Antihistamine drugs act by blocking the action of histamine on nerve endings. Submit Feedback.
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Mast cell s respond to mechanical or chemical irritation by discharging…. Mast cells play an important protective role and have been observed as being intimately involved in wound healing and defense against pathogens.
They play an important role in helping defend these tissues from disease. Mast cells play a major role in many physiologic processes, but for reasons that are unclear, they may become an aggressive force, which can damage the natural biologic balance. German medical scientist Paul Ehrlich was the first to describe mast cells, doing so in his doctoral thesis 1878.
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More research is needed. THE BAD With continuing research into mast cells, new insights are being developed and the list of conditions, disorders and diseases that include mast cell involvement is growing.
Please consider donating to your preferred cause in the name of research. Mast cells are "master regulators" of the immune system. As described by The Mastocytosis Society , there are two main forms of mast cell disorders: Researchers also think mast cells may have a role in the growth of blood vessels angiogenesis.Type I hypersensitivity (IgE-mediated hypersensitivity) - causes, symptoms, pathology
These symptoms are treated with medications including antihistamines, mast cell stabilizers, and leukotriene inhibitors, while anaphylaxis is a medical emergency requiring epinephrine. Autoimmunity Mast cells are implicated in the pathology associated with the autoimmune disorders rheumatoid arthritis , bullous pemphigoid , and multiple sclerosis. View "Mast Cells — Visual Perspectives".